{"id":10982,"date":"2023-12-04T13:57:00","date_gmt":"2023-12-04T18:57:00","guid":{"rendered":"https:\/\/torontoneckandbackpain.com\/?p=10982"},"modified":"2023-12-04T13:57:00","modified_gmt":"2023-12-04T18:57:00","slug":"in-depth-review-of-spinal-manipulation","status":"publish","type":"post","link":"https:\/\/torontoneckandbackpain.com\/newsite\/in-depth-review-of-spinal-manipulation\/","title":{"rendered":"In-depth Review of Spinal Manipulation"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Spinal manipulation is one of the most ancient forms of treatment for musculoskeletal <\/span><span style=\"font-weight: 400;\">complaints, primarily for back pain and neck pain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In 1992, Robert Anderson, MD, PhD, DC, was the Director of Manual Medicine at the San <\/span><span style=\"font-weight: 400;\">Francisco Spine Institute, as well as Professor of Anthropology at Mills College in Oakland, <\/span><span style=\"font-weight: 400;\">California.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">At that time (1992), Scott Haldeman, DC, PhD, MD, was Associate Clinical Professor of <\/span><span style=\"font-weight: 400;\">Neurology at the University of California, Irvine, California.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In 1992, the second edition of Dr. Haldeman\u2019s book, Principles and Practice of Chiropractic, was <\/span><span style=\"font-weight: 400;\">published. Dr. Anderson wrote the first chapter of Dr. Haldeman\u2019s book, titled (1):<\/span><\/p>\n<h5><em><strong>\u201cSpinal Manipulation Before Chiropractic\u201d<\/strong><\/em><\/h5>\n<p><span style=\"font-weight: 400;\">Dr. Anderson notes that historically (for a least 2,500 years), spinal manipulation had been <\/span><span style=\"font-weight: 400;\">practiced in many parts of the world, primarily to treat musculoskeletal disorders. He presents <\/span><span style=\"font-weight: 400;\">the evidence of spinal manipulation being applied by a variety of providers in vast geographic <\/span><span style=\"font-weight: 400;\">regions, including: Bohemian (Czechoslovakia), China, Egypt, England, Finland, Greece, India, <\/span><span style=\"font-weight: 400;\">Japan, Latin America, Norway, Russia, and Wales.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In many ways, the history of joint manipulation parallels the history of civilization. Another <\/span><span style=\"font-weight: 400;\">important review of manipulation through the ages was published in The Journal of Manual &amp;amp; <\/span><span style=\"font-weight: 400;\">Manipulative Therapy in 2007 and titled (2):<\/span><\/p>\n<h5><em><strong>A History of Manipulative Therapy<\/strong><\/em><\/h5>\n<p><span style=\"font-weight: 400;\">This review makes these comments:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cManipulative therapy has known a parallel development throughout many parts of the world. <\/span><span style=\"font-weight: 400;\">The earliest historical reference to the practice of manipulative therapy in Europe dates back to <\/span><span style=\"font-weight: 400;\">400 BCE.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cHistorically, manipulation can trace its origins from parallel developments in many parts <\/span><span style=\"font-weight: 400;\">of the world where it was used to treat a variety of musculoskeletal conditions, including <\/span><span style=\"font-weight: 400;\">spinal disorders.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIt is acknowledged that spinal manipulation is and was widely practiced in many cultures <\/span><span style=\"font-weight: 400;\">and often in remote world communities such as by the Balinese of Indonesia, the Lomi- <\/span><span style=\"font-weight: 400;\">Lomi of Hawaii, in areas of Japan, China and India, by the shamans of Central Asia, by <\/span><span style=\"font-weight: 400;\">sabodors in Mexico, by bone setters of Nepal as well as by bone setters in Russia and <\/span><span style=\"font-weight: 400;\">Norway.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cHistorical reference to Greece provides the first direct evidence of the practice of spinal <\/span><span style=\"font-weight: 400;\">manipulation.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cHippocrates (460\u2013385 BCE), who is often referred to as the father of medicine, was the <\/span><span style=\"font-weight: 400;\">first physician to describe spinal manipulative techniques.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cClaudius Galen (131\u2013202 CE), a noted Roman surgeon, provided evidence of <\/span><span style=\"font-weight: 400;\">manipulation including the acts of standing or walking on the dysfunctional spinal region.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cAvicenna (also known as the doctor of doctors) from Baghdad (980\u20131037 CE) included <\/span><span style=\"font-weight: 400;\">descriptions of Hippocrates\u2019 techniques in his medical text The Book of Healing.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cNobody questions these early origins of manipulative therapy.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Prior to the modern era, for hundreds of years in developed and primitive societies throughout <\/span><span style=\"font-weight: 400;\">the world, practitioners of manipulation were known as bonesetters (2). All of this changed in <\/span><span style=\"font-weight: 400;\">1874, and the global seat of change was in the United States of America.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Andrew Taylor Still was a second-generation physician who became disillusioned with medicine <\/span><span style=\"font-weight: 400;\">following the death (from disease) of three of his children. Dr. Still conceived a theory whereby <\/span><span style=\"font-weight: 400;\">health could only be maintained and, therefore, disease defeated, by maintaining normal function <\/span><span style=\"font-weight: 400;\">of the musculoskeletal system (2). In 1892, Still established the American Osteopathic College in <\/span><span style=\"font-weight: 400;\">Kirksville, Missouri. By the time of his death in 1917, 3,000 Doctors of Osteopathy had <\/span><span style=\"font-weight: 400;\">graduated from his school.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In 1895, \u201cnatural healer\u201d Daniel David (DD) Palmer reasoned that when a vertebra was out of <\/span><span style=\"font-weight: 400;\">alignment, it caused pressure on nerves. In 1897, Palmer opened his first college, The Palmer <\/span><span style=\"font-weight: 400;\">College of Cure, now known as Palmer College of Chiropractic, Davenport, Iowa (2).\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In 1910, Palmer\u2019s son Bartlett Joshua (BJ) Palmer, introduced the use of X-rays into <\/span><span style=\"font-weight: 400;\">Chiropractic. History records (2):<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe G. I. Bill at the end of World War II enabled thousands of returning soldiers to <\/span><span style=\"font-weight: 400;\">bolster the ranks of the chiropractic profession.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThis influx seemed to provide an impetus that would propel the chiropractic profession to <\/span><span style=\"font-weight: 400;\">today\u2019s status where it boasts 35 schools and colleges worldwide and, in the Western world <\/span><span style=\"font-weight: 400;\">at least, it is second only to the medical profession as a primary care healthcare provider.\u201d<\/span><\/p>\n<h4><strong>How Does Spinal Manipulation Work?<br \/>\n<\/strong><\/h4>\n<p><span style=\"font-weight: 400;\">Pain Theory Background (This blog post is a re-print from our sister blog site which can be found here https:\/\/www.dkchiroblog.com\/1717\/the-effects-of-spinal-manipulation-on-the-musculoskeletal-system\/)<br \/>\n<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In 2017, a comprehensive and authoritative assessment of the chiropractic profession appeared in <\/span><span style=\"font-weight: 400;\">the orthopedic medical journal Spine, titled (3):<\/span><\/p>\n<h5><em><strong>The Prevalence, Patterns, and Predictors of Chiropractic Use Among US Adults:<\/strong><\/em><\/h5>\n<p><span style=\"font-weight: 400;\">Results From the 2012 National Health Interview Survey<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The survey results indicated that 93% of patients go to chiropractors for the management of <\/span><span style=\"font-weight: 400;\">musculoskeletal pain syndromes. Specifically, 63% go to chiropractors for low back pain, and <\/span><span style=\"font-weight: 400;\">30% for neck pain. Additionally, chiropractic spinal manipulation is very effective for the <\/span><span style=\"font-weight: 400;\">management of back and neck pain (3). The study showed:<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">65% of the patients reported that chiropractic care helped their condition \u201ca great deal.\u201d<\/span><\/li>\n<li><span style=\"font-weight: 400;\">26% of the patients reported that chiropractic care helped their condition \u201csomewhat.\u201d<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Only 3% reported that the chiropractic care they received did not help them.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In randomized clinical trials comparing chiropractic spinal manipulation to prescription pain <\/span><span style=\"font-weight: 400;\">medicines for chronic low back and neck pain, chiropractic manipulation was significantly more <\/span><span style=\"font-weight: 400;\">effective, registered no significant side effects, and displayed stable long-term clinical benefits <\/span><span style=\"font-weight: 400;\">(at the one year follow-up assessment) (4, 5).<\/span><\/p>\n<h5><strong>How does chiropractic spinal manipulation benefit people with spinal pain complaints?<\/strong><\/h5>\n<h4><span style=\"font-weight: 400;\"><br \/>\n<\/span><strong>The Concept of Proprioception<\/strong><\/h4>\n<p><span style=\"font-weight: 400;\">Proprioception is a sensory input from the peripheral musculoskeletal body (muscles, joints, <\/span><span style=\"font-weight: 400;\">tendons, ligaments, etc.) to the brain (central nervous system). Proprioceptive signals transmit <\/span><span style=\"font-weight: 400;\">mechanical information, especially mechanical factors such as position and movement. This <\/span><span style=\"font-weight: 400;\">concept is well-stated by attorney Chris Crowley and physician Henry Lodge, MD, in their book<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Younger Next Year, in a section they refer to as (6):<\/span><\/p>\n<h5><em><strong>\u201cThe Balancing Act\u201d<\/strong><\/em><\/h5>\n<p><span style=\"font-weight: 400;\">\u201cNow it\u2019s time to think about your brain and a concept called proprioception\u2014the <\/span><span style=\"font-weight: 400;\">deceptively simple notion that you have to know where the different parts of your body are <\/span><span style=\"font-weight: 400;\">at all times.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cYour body is aware of exactly where each limb is in space every second, because each <\/span><span style=\"font-weight: 400;\">muscle, tendon, ligament and joint sends thousands of nerve fibers back to the brain <\/span><span style=\"font-weight: 400;\">through the spinal cord. Those fibers signal every nuance gradation of contraction, <\/span><span style=\"font-weight: 400;\">strength, muscular tone, orientation, position and movement at every moment of the day.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cYour brain keeps careful track of the location of every muscle and joint in you body every <\/span><span style=\"font-weight: 400;\">second, all day, every day, waiting for you to need the information.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Proprioception is both conscious and subconscious. In 1965, researchers discovered an <\/span><span style=\"font-weight: 400;\">incredibly important function for proprioception: pain control.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In 1965, pain researchers became aware that the proprioceptive signals to the brain could block <\/span><span style=\"font-weight: 400;\">the pain signal to the brain. This concept was originally proposed by pain researchers Ronald <\/span><span style=\"font-weight: 400;\">Melzack and Patrick Wall (7). Their theory is known as the Gate Control Theory of Pain. Ronald <\/span><span style=\"font-weight: 400;\">Melzack, PhD, is a Canadian psychologist. Patrick Wall, MD (d. 2001), was a British <\/span><span style=\"font-weight: 400;\">neuroscientist and pain expert, as well as the first editor of the journal Pain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In 2002, the British Journal of Anaesthesia published a study reaffirming the validity of the Gate <\/span><span style=\"font-weight: 400;\">Theory of Pain in an article titled (8):<\/span><\/p>\n<h5><em><strong>Gate Control Theory of Pain Stands the Test of Time<\/strong><\/em><\/h5>\n<p><span style=\"font-weight: 400;\">An oversimplified explanation of their Gate Control Theory of Pain is that the pain electrical <\/span><span style=\"font-weight: 400;\">signal to the brain can be blocked by non-painful electrical signals arising from other sensory <\/span><span style=\"font-weight: 400;\">afferents, especially from joint proprioceptors. Practically, this would mean that prolonged or <\/span><span style=\"font-weight: 400;\">static positions would reduce proprioception, allowing the pain signal to more readily enter the <\/span><span style=\"font-weight: 400;\">brain for pain perception. Similarity, if a person\u2019s joints lost or reduced their normal movement <\/span><span style=\"font-weight: 400;\">arc, there would be a proportionate reduction of the proprioceptive sensory input to the brain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This would allow pain signals to enter the brain because the pain gate would be open. <\/span><span style=\"font-weight: 400;\">As noted above, chiropractic\u2019s Daniel David Palmer believed that when a vertebra was out of <\/span><span style=\"font-weight: 400;\">alignment, it caused pressure on nerves (2). A specific directional manipulation (the chiropractic <\/span><span style=\"font-weight: 400;\">spinal adjustment) would improve alignment and reduce nerve pressure.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Palmer\u2019s \u201cnerve pressure\u201d theory is probably correct in only a minority of chiropractic patients. <\/span><span style=\"font-weight: 400;\">It was officially challenged by a vocally pro-chiropractic orthopedic surgeon from <\/span><span style=\"font-weight: 400;\">Saskatchewan, CAN. Dr. William H. Kirkaldy-Willis published his theory as to how\/why <\/span><span style=\"font-weight: 400;\">chiropractic spinal manipulation helped those suffering from back pain in the journal Canadian <\/span><span style=\"font-weight: 400;\">Family Physician in 1985 (35 years prior to this writing), titled (9):<\/span><\/p>\n<h5><em><strong>Spinal Manipulation in the Treatment of Low Back Pain<\/strong><\/em><\/h5>\n<p><span style=\"font-weight: 400;\">Dr. Kirkaldy-Willis (d. 2006) was a Professor Emeritus of Orthopedics and director of the Low-<\/span><span style=\"font-weight: 400;\">Back Pain Clinic at the University Hospital, Saskatoon, Canada. The abstract from his article <\/span><span style=\"font-weight: 400;\">makes these comments:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cSpinal manipulation, one of the oldest forms of therapy for back pain, has mostly been <\/span><span style=\"font-weight: 400;\">practiced outside of the medical profession.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cOver the past decade, there has been an escalation of clinical and basic science research on <\/span><span style=\"font-weight: 400;\">manipulative therapy, which has shown that there is a scientific basis for the treatment of <\/span><span style=\"font-weight: 400;\">back pain by manipulation.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cMost family practitioners have neither the time nor inclination to master the art of <\/span><span style=\"font-weight: 400;\">manipulation and will wish to refer their patients to a skilled practitioner of this therapy.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe physician who makes use of this resource will provide relief for many patients.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Kirkaldy-Willis notes that 80% of the population will experience low back pain sometime <\/span><span style=\"font-weight: 400;\">during their adult life. At any given time, 20-30% of the adult population is suffering from low <\/span><span style=\"font-weight: 400;\">back pain. Low back pain is the second most common cause of worker loss of productivity.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Yet, in disagreement with chiropractic\u2019s Daniel David Palmer, Dr. Kirkaldy-Willis argues that <\/span><span style=\"font-weight: 400;\">less than 10% of low back pain is due to pressure or entrapment of spinal nerves. He notes that it <\/span><span style=\"font-weight: 400;\">is unlikely that spinal manipulation replaces a vertebra that is out of alignment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In contrast, Dr. Kirkaldy-Willis applies Melzack and Wall\u2019s Gate Theory of Pain to the <\/span><span style=\"font-weight: 400;\">chiropractic adjustment in his explanation as to how manipulation helps with pain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Kirkaldy-Willis begins his explanation by noting that with positional (alignment) problems <\/span><span style=\"font-weight: 400;\">there is a shortening of periarticular connective tissues and intra-articular adhesions may form.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This orthopedic principle is supported by many others (10, 11, 12, 13, 14, 15, 16, 17, 17). This <\/span><span style=\"font-weight: 400;\">intra-articular and periarticular fibrosis would reduce joint motion. He proposes that a specific <\/span><span style=\"font-weight: 400;\">line-of-drive manipulation (chiropractic spinal adjustment) could break these adhesions and\/or <\/span><span style=\"font-weight: 400;\">remodel fibrosis, also supported by others (11, 12, 13, 15, 16, 17, 18). He cites support for these<\/span><span style=\"font-weight: 400;\">concepts, including:<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Following joint manipulation, there is consistently a measureable increase in the range of <\/span>motion.<\/li>\n<li>As a rule, there is an initial increase in symptoms after the first few manipulations probably as a result of breaking adhesions and tissue fibrosis. He states:<\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">\u201cIn almost all cases, however, this increase in pain is temporary and can be easily controlled by <\/span><span style=\"font-weight: 400;\">local application of ice.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cPatients undergoing manipulative treatment must therefore be reassured that the initial <\/span><span style=\"font-weight: 400;\">discomfort is only temporary.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cHowever, the gain in mobility must be maintained during this period to prevent further adhesion <\/span><span style=\"font-weight: 400;\">formation.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Kirkaldy-Willis then applies the improved articular motion to Melzack and Wall\u2019s Gate <\/span><span style=\"font-weight: 400;\">Theory of Pain. He notes that this theory has \u201cwithstood rigorous scientific scrutiny,\u201d stating:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe central transmission of pain can be blocked by increased proprioceptive input.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pain is facilitated by \u201clack of proprioceptive input.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIncreased proprioceptive input in the form of spinal mobility tends to decrease the central <\/span><span style=\"font-weight: 400;\">transmission of pain from adjacent spinal structures by closing the gate. Any therapy <\/span><span style=\"font-weight: 400;\">which induces motion into articular structures will help inhibit pain transmission by this <\/span><span style=\"font-weight: 400;\">means.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dr. Kirkaldy-Willis notes that at the end of the manipulation range of motion, \u201cthe limit of <\/span><span style=\"font-weight: 400;\">anatomical integrity is encountered. Movement beyond this limit results in damage to the <\/span><span style=\"font-weight: 400;\">capsular ligaments.\u201d Consequently, joint manipulation \u201crequires precise positioning of the joint <\/span><span style=\"font-weight: 400;\">at the end of the passive range of motion and the proper degree of force to overcome joint <\/span><span style=\"font-weight: 400;\">coaptation\u201d (to overcome the resistance of the joint surfaces in contact). He concludes:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cWith experience, the manipulator can be very specific in selecting the spinal level to be<\/span><span style=\"font-weight: 400;\">manipulated.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe physician who makes use of this resource will provide relief for many back pain patients.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Today (2020) this \u201cOrthopedic Gate Theory\u201d explanation for the mechanism of benefits from <\/span><span style=\"font-weight: 400;\">manipulation for pain control is widely popular. Yet, Dr. Kirkaldy-Willis also offers a <\/span><span style=\"font-weight: 400;\">concomitant reflex neurological model. He supports that during manipulation, the stretching of <\/span><span style=\"font-weight: 400;\">joint ligaments (capsules) will trigger a reflex that inhibits local musculature, also improving <\/span><span style=\"font-weight: 400;\">motion and closing the pain gate.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022<\/span><\/p>\n<p><span style=\"font-weight: 400;\">An update to the effects of spinal manipulation was published last year (2019) in the journal <\/span><span style=\"font-weight: 400;\">Spine, titled (19):<\/span><\/p>\n<h5><em><strong>Neurophysiological Effects of High Velocity and Low Amplitude Spinal Manipulation in Symptomatic and Asymptomatic Humans:<\/strong><\/em><\/h5>\n<p>&nbsp;<\/p>\n<h4><strong>A Systematic Literature Review<\/strong><\/h4>\n<p><span style=\"font-weight: 400;\">The objective of this study was to summarize the evidence of the neurophysiological effects of <\/span><span style=\"font-weight: 400;\">spinal manipulative therapy (SMT) with high velocity low amplitude thrust (HVLA-SMT). The <\/span><span style=\"font-weight: 400;\">authors searched the literature until July 2018 and only used controlled studies of at least <\/span><span style=\"font-weight: 400;\">moderate quality. They found 18 studies that met their inclusion criteria that involved 932 <\/span><span style=\"font-weight: 400;\">participants. Most studies on spinal manipulation focus on pain mechanisms and pain control.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The authors note that spinal manipulative therapy with high-velocity low amplitude thrust <\/span><span style=\"font-weight: 400;\">(HVLA-SMT) is effective in reducing low back pain (LBP), and applies to both acute and <\/span><span style=\"font-weight: 400;\">chronic nonspecific LBP. They agree that spinal manipulation has both neurophysiological and <\/span><span style=\"font-weight: 400;\">biomechanical influences, and support that manipulation increases proprioception, stating:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe mechanical force of spinal manipulation primarily affects afferent neurons in the <\/span><span style=\"font-weight: 400;\">paraspinal tissue and triggers neurophysiological responses in the peripheral and central <\/span><span style=\"font-weight: 400;\">nervous system, eventually leading to pain inhibition.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The evidence presented in this study supports that spinal manipulation increases proprioception, <\/span><span style=\"font-weight: 400;\">which eventually leads to pain inhibition. This is consistent and supportive of Dr. Kirkaldy-<\/span><span style=\"font-weight: 400;\">Willis\u2019s application of Melzack and Wall\u2019s Gate Theory of Pain, above.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Also in 2019 (April), a study was published in the Journal of Pain titled (20):<\/span><\/p>\n<h5><em><strong>Decreased Neurologic Pain Signature Activation Following Thoracic Spine Manipulation in Healthy Volunteers<\/strong><\/em><\/h5>\n<p><span style=\"font-weight: 400;\">In this study, researchers from Stanford University employed functional magnetic resonance <\/span><span style=\"font-weight: 400;\">imaging (fMRI) on ten healthy volunteers to objectively measure pain intensity following spinal <\/span><span style=\"font-weight: 400;\">manipulation. This study was funded by the National Institute of Health, USA.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The authors note that: \u201cSpinal manipulation is commonly used when managing patients with <\/span><span style=\"font-weight: 400;\">neck and back pain.\u201d Although they support the rationale that spinal manipulation elicits a <\/span><span style=\"font-weight: 400;\">mechanical effect on the spine that leads to therapeutic mechanical changes within the spine, <\/span><span style=\"font-weight: 400;\">they wanted to explore if central (brain) mechanisms were also being activated. The results of <\/span><span style=\"font-weight: 400;\">this study showed that spinal manipulation activates brain regions associated with pain <\/span><span style=\"font-weight: 400;\">inhibition.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It has been observed for decades that spinal manipulation helps control pain. This study adds to <\/span><span style=\"font-weight: 400;\">the evidence, using the best available evidence (functional MRI), showing that spinal <\/span><span style=\"font-weight: 400;\">manipulation works in pain reduction, in part, by inhibiting pain-processing regions of the brain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Once again, the results of this study are consistent and supportive of Dr. Kirkaldy-Willis\u2019s <\/span><span style=\"font-weight: 400;\">application of Melzack and Wall\u2019s Gate Theory of Pain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022<\/span><\/p>\n<p><span style=\"font-weight: 400;\">A few months later in 2019 (October), this same group published a follow-up study titled (21):<\/span><\/p>\n<h5><em><strong>Evidence for Decreased Neurologic Pain Signature Activation<\/strong><\/em><\/h5>\n<p>&nbsp;<\/p>\n<h4><strong>Following Thoracic Spinal Manipulation in Healthy Volunteers and Participants with Neck Pain<\/strong><\/h4>\n<p><span style=\"font-weight: 400;\">Once again, these authors used functional magnetic resonance imaging (fMRI) to investigate the <\/span><span style=\"font-weight: 400;\">effect of thoracic spinal manipulation on pain-related brain activity. They assessed 16 subjects <\/span><span style=\"font-weight: 400;\">with acute\/subacute neck pain and compared them to 10 healthy volunteers. The spinal <\/span><span style=\"font-weight: 400;\">manipulation was a high-velocity low-amplitude end-range force directed to the T4-T5 motion <\/span><span style=\"font-weight: 400;\">segment. The brain fMRI images were performed on a 3T magnetic resonance scanner.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The authors note that fMRIs can map pain processing in the central nervous system. They also <\/span><span style=\"font-weight: 400;\">note that the perception of pain is not encoded by a single brain area but distributed throughout <\/span><span style=\"font-weight: 400;\">the brain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Spinal manipulation is a mechanical thrust to spinal joints slightly beyond their passive range of <\/span><span style=\"font-weight: 400;\">motion. It is a common treatment for neck and back pain, theorized to mechanically affect the <\/span><span style=\"font-weight: 400;\">spine leading to therapeutic mechanical changes. Yet, spinal manipulation\u2019s therapeutic action <\/span><span style=\"font-weight: 400;\">may also be mediated by inhibiting the central nervous system.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This study confirmed that there is a centrally (brain) mediated therapeutic action of spinal <\/span><span style=\"font-weight: 400;\">manipulation for pain reduction. The authors note:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe findings provide evidence that spinal manipulation may alter the processing of pain- <\/span><span style=\"font-weight: 400;\">related brain activity within specific pain-related brain regions.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cA growing body of evidence is pointing towards neurophysiologic mechanisms of action <\/span><span style=\"font-weight: 400;\">underlying the pain modulating effects of spinal manipulation including both spinal and <\/span><span style=\"font-weight: 400;\">supraspinal mechanisms.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Consistent with the other studies above, and in support of the proprioception closure of the pain <\/span><span style=\"font-weight: 400;\">gate, these authors note:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cSpinal manipulation is known to activate large diameter mechanoreceptors that in turn <\/span><span style=\"font-weight: 400;\">can inhibit the transmission of nociceptive signals at the spinal cord.\u201d<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022\u2022<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Earlier this year (2020), another study on this topic was published in the journal Cureus titled<\/span><span style=\"font-weight: 400;\">(22):<\/span><\/p>\n<h5><em><strong>The Effect of High Velocity Low Amplitude Cervical Manipulations on the Musculoskeletal System:<\/strong><\/em><\/h5>\n<h4><strong>Literature Review<\/strong><\/h4>\n<p><span style=\"font-weight: 400;\">As the title indicates, the objective of the study was to describe how cervical manipulation could <\/span><span style=\"font-weight: 400;\">impact musculoskeletal disorders. A systematic search of the literature was carried out using <\/span><span style=\"font-weight: 400;\">PubMed; inclusion criteria was randomized controlled trial manuscripts published in peer-<\/span><span style=\"font-weight: 400;\">reviewed journals with individuals of all ages from 2005 to 2020. Subjects with skeletal muscle <\/span><span style=\"font-weight: 400;\">or health problems were evaluated as to the effects of cervical manipulation, comparing them <\/span><span style=\"font-weight: 400;\">with control subjects receiving placebo or another type of treatment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The authors note that the number of people suffering from skeletal muscle problems is constantly <\/span><span style=\"font-weight: 400;\">increasing. They attribute this to work activities that lead to prolonged wrong positions for a <\/span><span style=\"font-weight: 400;\">period of time.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pertaining to spinal manipulation, the authors note:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cSpinal manipulation is a manual therapy technique used by chiropractors, osteopaths, <\/span><span style=\"font-weight: 400;\">physiotherapists and some doctors to treat skeletal muscle problems.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIn manual therapy, high velocity low amplitude (HVLA) cervical manipulation techniques <\/span><span style=\"font-weight: 400;\">are frequently used.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe use of high velocity low amplitude (HVLA) techniques is growing as a therapeutic\u00a0<\/span><span style=\"font-weight: 400;\">option.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cCervical manipulations are effective in management of cervicalgia, epicondylalgia, <\/span><span style=\"font-weight: 400;\">temporomandibular joint disorders, and shoulder pain.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Both cervical manipulation and thoracic manipulation may lead to significant cervical pain <\/span><span style=\"font-weight: 400;\">improvement. The review of the literature presented indicates that spinal manipulation activates <\/span><span style=\"font-weight: 400;\">the supraspinal (brain and brainstem) neurological pain inhibitory control system. The authors <\/span><span style=\"font-weight: 400;\">note:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cManipulation involves segmental activation of inhibitory pathways that may lead to <\/span><span style=\"font-weight: 400;\">changes in pressure pain thresholds even at a distance [away from] of the manipulated <\/span><span style=\"font-weight: 400;\">area.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cHVLA techniques are able to produce more local hypoalgesia than other manual therapy <\/span><span style=\"font-weight: 400;\">techniques.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe results of the research show that HVLA techniques, on subjects with musculoskeletal <\/span><span style=\"font-weight: 400;\">disorders, are able to influence pain modulation, mobility, and strength both in the treated <\/span><span style=\"font-weight: 400;\">area and at a distance.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For thousands of years and throughout the world there are observations that spinal manipulation <\/span><span style=\"font-weight: 400;\">helps people with musculoskeletal pain, especially spinal pain. For more than one hundred years, <\/span><span style=\"font-weight: 400;\">chiropractors, patients, governments, insurance companies, and scientists have realized that <\/span><span style=\"font-weight: 400;\">chiropractic spinal adjusting (specific manipulation) not only helps people with a variety of <\/span><span style=\"font-weight: 400;\">musculoskeletal pain syndromes, but that it probably works, at least in part, as a consequence of <\/span><span style=\"font-weight: 400;\">the activation of brain pain control circuitry.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When spinal joints have reduced movement, the pain gate at that level is open. Chiropractic <\/span><span style=\"font-weight: 400;\">adjusting (specific manipulation) increases the firing of the proprioceptors, creating a <\/span><span style=\"font-weight: 400;\">neurological sequence of events that closes the pain gate.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Proprioceptive integrity is a significant factor in the state of the pain gate. Improved <\/span><span style=\"font-weight: 400;\">proprioception closes the pain gate. Chiropractic adjusting improves proprioception.<\/span><\/p>\n<h4><strong>REFERENCES:<\/strong><\/h4>\n<ol>\n<li><span style=\"font-weight: 400;\"> Anderson R; \u201cSpinal Manipulation Before Chiropractic\u201d; in Haldeman S; Principles and <\/span>Practice of Chiropractic; Second Edition; Appleton &amp;amp; Lang; 1992.<\/li>\n<\/ol>\n<ol start=\"2\">\n<li><span style=\"font-weight: 400;\"> Pettman E; A History of Manipulative Therapy; The Journal of Manual &amp;amp; Manipulative <\/span>Therapy; Vol. 15; No. 3; (2007); pp. 165\u2013174.<\/li>\n<\/ol>\n<ol start=\"3\">\n<li><span style=\"font-weight: 400;\"> Adams J, Peng W, Cramer H, Sundberg T, Moore C; The Prevalence, Patterns, and <\/span>Predictors of Chiropractic Use Among US Adults; Results From the 2012 National Health Interview Survey; Spine; December 1, 2017; Vol. 42; No. 23; pp. 1810\u20131816.<\/li>\n<\/ol>\n<ol start=\"4\">\n<li><span style=\"font-weight: 400;\"> Giles LGF; Muller R; Chronic Spinal Pain: A Randomized Clinical Trial Comparing <\/span>Medication, Acupuncture, and Spinal Manipulation; Spine July 15, 2003; Vol. 28; No. 14; pp. 1490-1502.<\/li>\n<\/ol>\n<ol start=\"5\">\n<li><span style=\"font-weight: 400;\"> Muller R, Giles LGF; Long-Term Follow-up of a Randomized Clinical Trial Assessing <\/span>the Efficacy of Medication, Acupuncture, and Spinal Manipulation for Chronic Mechanical Spinal Pain Syndromes; Journal of Manipulative and Physiological Therapeutics; January 2005; Vol. 28; No. 1; pp. 3-11.<\/li>\n<\/ol>\n<ol start=\"6\">\n<li><span style=\"font-weight: 400;\"> Crowley C, Henry Lodge H; Younger Next Year: Live Strong, Fit, and Sexy\u2014Until <\/span>You\u2019re 80 and Beyond; Workman Publishing; New York; 2007.<\/li>\n<\/ol>\n<ol start=\"7\">\n<li><span style=\"font-weight: 400;\"> Melzack R, Wall P; Pain mechanisms: a new theory; Science; November 19, <\/span>1965;150(3699); pp. 971-979.<\/li>\n<\/ol>\n<ol start=\"8\">\n<li><span style=\"font-weight: 400;\"> Dickenson AH; Gate Control Theory of Pain Stands the Test of Time; British Journal of <\/span>Anaesthesia; June 2002; Vol. 88; No. 6; pp. 755-757.<\/li>\n<\/ol>\n<ol start=\"9\">\n<li><span style=\"font-weight: 400;\"> Kirkaldy-Willis WH, Cassidy JD; Spinal Manipulation in the Treatment of Low Back <\/span>Pain; Canadian Family Physician; March 1985; Vol. 31; pp. 535-540.<\/li>\n<\/ol>\n<ol start=\"10\">\n<li><span style=\"font-weight: 400;\"> Viderman T; Experimental Models of Osteoarthritis: The Role of Immobilization; <\/span>Clinical Biomechanics; November 1987; Vol. 2; No. 4; pp. 223-229.<\/li>\n<\/ol>\n<ol start=\"11\">\n<li><span style=\"font-weight: 400;\"> Stearns, ML; Studies on development of connective tissue in transparent chambers in <\/span>rabbit\u2019s ear; American Journal of Anatomy; Vol. 67; 1940; p. 55.<\/li>\n<\/ol>\n<ol start=\"12\">\n<li><span style=\"font-weight: 400;\"> Seletz E; Whiplash Injuries: Neurophysiological Basis for Pain and Methods Used for <\/span>Rehabilitation; Journal of the American Medical Association; November 29, 1958; pp.1750-1755.<\/li>\n<\/ol>\n<ol start=\"13\">\n<li><span style=\"font-weight: 400;\"> Cyriax J; Orthopaedic Medicine, Diagnosis of Soft Tissue Lesions; Bailliere Tindall; Vol.<\/span>1; 1982.<\/li>\n<\/ol>\n<ol start=\"14\">\n<li><span style=\"font-weight: 400;\"> Cohen IK, Diegelmann RF, Lindbald WJ; Wound Healing, Biochemical &amp;amp; Clinical <\/span>Aspects; WB Saunders; 1992.<\/li>\n<\/ol>\n<ol start=\"15\">\n<li><span style=\"font-weight: 400;\"> Salter R; Continuous Passive Motion, A Biological Concept for the Healing and <\/span>Regeneration of Articular Cartilage, Ligaments, and Tendons; From Origination to Research to Clinical Applications; Williams and Wilkins; 1993.<\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<ol start=\"16\">\n<li><span style=\"font-weight: 400;\"> Buckwalter J; Effects of Early Motion on Healing of Musculoskeletal Tissues; Hand <\/span>Clinics; February 1996; Vol. 12; No. 1; pp. 13-24.<\/li>\n<\/ol>\n<ol start=\"17\">\n<li><span style=\"font-weight: 400;\"> Schleip R; Fascia; The Tensional Network of the Human Body; The Scientific and <\/span>Clinical Applications in Manual and Movement Therapy; Churchill Livingstone; 2012.<\/li>\n<\/ol>\n<ol start=\"18\">\n<li><span style=\"font-weight: 400;\"> Bowman K; Move Your DNA: Restore Your Health Through Natural Movement; 2017.<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Wirth B, Gassner A, de Bruin ED, Axen I, Swanenburg J, Kim Humphreys BK, <\/span>Schweinhardt P; Neurophysiological Effects of High Velocity and Low Amplitude Spinal Manipulation in Symptomatic and Asymptomatic Humans: A Systematic LiteratureReview; Spine; August 2019; Vol. 44; No. 15; pp. E914\u2013E926.<\/li>\n<\/ol>\n<ol start=\"20\">\n<li><span style=\"font-weight: 400;\"> Weber K, Wager T, Elliott J, Mackey S, Liu W, Sparks C; Decreased Neurologic Pain <\/span>Signature Activation Following Thoracic Spine Manipulation in Healthy Volunteers; TheJournal of Pain; April 2019; Vol. 20; No. 4; Supplement; p. S69.<\/li>\n<\/ol>\n<ol start=\"21\">\n<li><span style=\"font-weight: 400;\"> Weber KA, Wager TD, Mackey S, Elliott JM; Evidence for Decreased Neurologic Pain <\/span>Signature Activation Following Thoracic Spinal Manipulation in Healthy Volunteers and Participants with Neck Pain; NeuroImage: Clinical; October 18, 2019; Volume 24;102042.<\/li>\n<\/ol>\n<ol start=\"22\">\n<li><span style=\"font-weight: 400;\"> Giacalone A, Febbi M, Magnifica F, Ruberti E; The Effect of High Velocity Low <\/span>Amplitude Cervical Manipulations on the Musculoskeletal System: Literature Review; Cureus; April 15, 2020; Vol. 12; No. 4; pp. e7682. \u201cAuthored by Dan Murphy, D.C.. Published by ChiroTrust\u00ae \u2013 This publication is not meant to offer treatment advice or protocols. Cited material is not necessarily the opinion of the author or publisher.\u201d<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Spinal manipulation is one of the most ancient forms of treatment for musculoskeletal complaints, primarily for back pain and neck pain. In 1992, Robert Anderson, MD, PhD, DC, was the Director of Manual Medicine at the San Francisco Spine Institute, as well as Professor of Anthropology at Mills College in Oakland, California. At that time [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":10799,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","footnotes":""},"categories":[112],"tags":[6,232,225,233,234,179,235,226,9,38,227,267,13],"class_list":["post-10982","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-others","tag-chiropractic","tag-chiropractor-davisville","tag-chiropractor-in-toronto","tag-chiropractor-midtown","tag-chiropractor-midtown-toronto","tag-chiropractor-near-me","tag-chiropractor-yonge-and-davisville","tag-davisville-chiropractor","tag-fix-my-back","tag-joint-pain","tag-midtown-chiropractor","tag-midtown-toronto-chiropractor","tag-toronto-chiropractor"],"_links":{"self":[{"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/posts\/10982","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/comments?post=10982"}],"version-history":[{"count":0,"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/posts\/10982\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/media\/10799"}],"wp:attachment":[{"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/media?parent=10982"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/categories?post=10982"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/torontoneckandbackpain.com\/newsite\/wp-json\/wp\/v2\/tags?post=10982"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}